8-iso-17-phenyl trinor Prostaglandin F2α

The C-8 epimer of bimatoprost (free acid)

原价

￥2850-22450

价格

￥ 2280-17960

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库存: 现货

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产品引用

货号: ajcx17638
CAS: N/A
别名: 8-iso-17-phenyl PGF2β
分子式: C23H32O5
分子量: 388.5
纯度: >98%
溶解度: DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 1 mg/ml
储存: Store at -20°C
库存: 现货

Background

8-iso-17-phenyl trinor Prostaglandin F2α (8-iso-17-phenyl trinor PGF2α) is the C-8 epimer of bimatoprost (free acid), a metabolically stable analog of PGF2α. Bimatoprost (free acid) binds to the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. At the rat recombinant FP receptor expressed in CHO cells bimatoprost inhibits PGF2α binding with a Ki of 1.1 nM. There are no published studies of the pharmacological properties of 8-iso-17-phenyl trinor PGF2α.

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信号通路

生命科学

有机化学

无机化学

材料科学

8-iso-17-phenyl trinor Prostaglandin F2α

8-iso-17-phenyl trinor Prostaglandin F2α详情

Background