(S)-(-)-Eicosapentaenyl-1'-Hydroxy-2'-Propylamide

一个与EPEA同源的物质。

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库存: 现货

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数量
1mg

￥1362.00

1090.00

- +
5mg

￥6025.00

4820.00

- +
10mg

￥10700.00

8560.00

- +

已选 0 种 0 瓶

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货号: ajcx17742
CAS: N/A
别名:
分子式: C23H37NO2
分子量: 359.6
纯度: >98%
溶解度: DMF: 11 mg/ml,DMSO: 10 mg/ml,Ethanol: 20 mg/ml,Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
储存: Store at -20°C
库存: 现货

Background

N-Acyl ethanolamines (NAEs) have diverse biological actions that are strongly affected by the associated acyl group. Eicosapentaenoyl ethanolamide (EPEA) has potential signaling roles in aging, cancer, inflammation, and neurological development.^1,2,3,4 At least some of EPEA’s effects are mediated through cannabinoid (CB) receptors, while some NAEs also act as vanilloid receptor agonists.^1,5 S-(?)-Eicosapentaenyl-1’-droxy-2’-propylamide is a homolog of EPEA, characterized by the addition of an (S)-α-metl group at the metlene carbon adjacent to the amide nitrogen. A similar modification of arachidonoyl ethanolamide to produce S-1 methanandamide results in a diminished affinity for the CB receptor but greatly improved metabolic stability to aminopeptidase drolysis.⁶ The psiological actions of this compound have not been evaluated.