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  • 15(R)-Prostaglandin I2 (sodium salt)
15(R)-Prostaglandin I2 (sodium salt)的可视化放大

15(R)-Prostaglandin I2 (sodium salt)

An isomer of PGI2

原价
¥1150-19575
价格
920-15660
15(R)-Prostaglandin I2 (sodium salt)的二维码

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  • 库存: 现货
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  • 货号: ajcx17796
  • CAS: N/A
  • 别名: 15(R)-PGI2
  • 分子式: C20H31O5?Na
  • 分子量: 374.5
  • 纯度: >98%
  • 溶解度: DMF: 5 mg/ml,DMSO: 5 mg/ml,PBS (pH 9.0): > 11 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

15(R)-Prostaglandin I2 (15(R)-PGI2) is an isomer of the natural 15(S) prostanoid, PGI2 . PGI2 is an unstable cyclooxygenase metabolite detected first in vascular endothelial cells. It elevates platelet cAMP and is a potent vasodilator and inhibitor of human platelet aggregation with an IC50 value of 5 nM. While the physiological properties of 15(R)-PGI2 are not well known, 15(R) isomers of PGs typically have reduced receptor agonist activity compared to their 15(S) forms.

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