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  3. 8-bromo-Cyclic ADP-Ribose (sodium salt)
  • 8-bromo-Cyclic ADP-Ribose (sodium salt)
8-bromo-Cyclic ADP-Ribose (sodium salt)的可视化放大

8-bromo-Cyclic ADP-Ribose (sodium salt)

An inhibitor of cADP-ribose signaling

原价
￥7787-7787
价格
￥ 6230-6230
8-bromo-Cyclic ADP-Ribose (sodium salt)的二维码

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  • 库存: 现货
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  • 货号: ajcx18012
  • CAS: N/A
  • 别名: 8-bromo-cADPR, 8-bromo-cADP-Ribose
  • 分子式: C15H18BrN5O13P2 ? 2Na
  • 分子量: 664.2
  • 纯度: >98%
  • 溶解度: Water: Soluble
  • 储存: Store at -20°C
  • 库存: 现货

Background

Cyclic ADP-ribose (cADP-ribose) is a calcium mobilizing nucleotide that is biosynthesized from NAD+ by cADP-ribose synthases, including CD38. cADP-Ribose appears to activate calcium channels in intracellular membranes, which in turn activate ryanodine receptors. 8-bromo-cADP-Ribose is a stable, cell-permeable analog that blocks calcium release evoked by cADP-ribose in sea urchin egg homogenates with an IC50 value of 1.7 µM. It is commonly used to investigate intracellular signaling through cADP-ribose in isolated cells and tissues.

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