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- Angiotensin Receptor
- Angiotensinogen (1-14) (human) (trifluoroacetate salt)
Angiotensinogen (1-14) (human) (trifluoroacetate salt)
A synthetic peptide precursor of angiotensin I
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1mg￥800.00640.00- +
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- 货号: ajcx18104
- CAS: N/A
- 别名:
- 分子式: C83H122N24O19?XCF3COOH
- 分子量: 1760
- 纯度: ＞98%
- 溶解度: Formic Acid: 1 mg/ml
- 储存: Store at -20°C
- 库存: 现货
Background
Angiotensinogen (1-14), also known as tetradecapeptide (TDP), is a synthetic peptide precursor of angiotensin I that corresponds to amino acids 1-14 of endogenous human angiotensinogen. Angiotensinogen (1-14) is cleaved by renin at the Leu-Val peptide bond to release angiotensin I, which is then converted to angiotensin II by angiotensin converting enzyme (ACE) and exerts vasoconstrictive properties. Angiotensinogen (1-14) (0.001-1 μM) induces contraction of isolated rat femoral resistance vessels, an effect that is reduced by the angiotensin II receptor partial antagonist saralasin and enhanced by the serine protease kallikrein.
