Atrial Natriuretic Peptide (3-28) (human) (trifluoroacetate salt)
An atrial natriuretic peptide
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包装价格促销价数量
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500ug￥2400.001920.00- +
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1mg￥4037.003230.00- +
- 货号: ajcx18120
- CAS: N/A
- 别名: ANP (3-28) (human)
- 分子式: C118H187N43O36S3?XCF3COOH
- 分子量: 2880.2
- 纯度: ＞98%
- 溶解度: Water: 1 mg/ml
- 储存: Store at -20°C
- 库存: 现货
Background
Atrial natriuretic peptide (ANP) (3-28) is a synthetic and truncated form of ANP, which is an endogenous peptide generated by proteolysis of prepro-ANP that is secreted by cardiomyocytes in the heart. ANP (3-28) potently inhibits renin release from cultured renal juxtaglomerular cells (Ki = 10 pM) in a cGMP-dependent manner. It also dose-dependently decreases mean arterial pressure (MAP) and arterial plasma renin activity and increases fractional sodium and calcium excretion, urine volume, and glomerular filtration rate in conscious dogs with a maximum effect attained when administered at a dose of 200 pM. ANP (3-28) (human) is a 26 amino acid peptide corresponding to the truncated human protein sequence.
