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  • CALP3 (trifluoroacetate salt)
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CALP3 (trifluoroacetate salt)

A calcium-like peptide

原价
¥3087-13637
价格
2470-10910
CALP3 (trifluoroacetate salt)的二维码

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  • 库存: 现货
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  • 货号: ajcx18232
  • CAS: N/A
  • 别名: Calcium-like peptide 3
  • 分子式: C44H68N10O9?XCF3COOH
  • 分子量: 881.1
  • 纯度: >98%
  • 溶解度: DMF: 5 mg/ml,DMSO: 5 mg/ml,Ethanol: 0.5 mg/ml,PBS (pH 7.2): 0.5 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

CALP3 is a calcium-like peptide that contains the first eight residues of CALP2, which is a 12-residue peptide that interacts with EF hand motif 4 in human calmodulin to activate it in the absence of calcium. It acts as a cell-permeable inhibitor of calcium influx through glutamate receptor channels in cultured rat neocortical neurons (IC50 = 37.25 µM) thereby inhibiting excitatory cytotoxicity (IC50 = 50.97 µM) and apoptosis (IC50 = 33.41 µM).

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