- 首页
- Cyclooxygenase (COX)
- CG 4305
CG 4305
A stable PGI2 analog with antithrombotic properties
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
-
包装价格促销价数量
-
100ug￥1687.001350.00- +
-
500ug￥7575.006060.00- +
-
1mg￥13325.0010660.00- +
已选
0
种
0
瓶
金额:
￥0.00
首页
收藏
- 货号: ajcx18262
- CAS: N/A
- 别名:
- 分子式: C25H32O4
- 分子量: 396.5
- 纯度: ＞98%
- 溶解度: DMF: 5 mg/ml,DMSO: 10 mg/ml,DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml,Ethanol: 3 mg/ml
- 储存: Store at -20°C
- 库存: 现货
Background
Prostacyclin (PGI2) is a cyclooxygenase metabolite with antithrombotic properties found in vascular endothelial cells. The half-life is short both in vivo and in vitro, ranging from 30 seconds to a few minutes. CG 4305 is a stable carbacyclic analog of PGI2 that inhibits ADP-induced platelet aggregation 25% at a concentration of 50 nM. Doses of 10 mg/kg (oral) or 1 mg/kg (intraduodenal) have been shown to prevent rabbit carotid artery thrombosis.
