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A corticostatic peptide
Corticostatin is a corticostatic peptide that has been found in human granulocytes. It inhibits corticosterone production stimulated by adrenocorticotropic hormone (ACTH) in rat adrenal cells (IC50 = 0.7 μM). Corticostatin also reduces mitogen-stimulated release of IFN-γ and IL-6 in human peripheral blood mononuclear cells (PBMCs).
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