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  • Defensin HNP-3 (human) (trifluoroacetate salt)
Defensin HNP-3 (human) (trifluoroacetate salt)的可视化放大

Defensin HNP-3 (human) (trifluoroacetate salt)

An antimicrobial peptide

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¥5125-5125
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4100-4100
Defensin HNP-3 (human) (trifluoroacetate salt)的二维码

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  • 货号: ajcx18322
  • CAS: N/A
  • 别名: DEFA3 Protein, α-Defensin 3, Human Neutrophil Peptide 3, Neutrophil Defensin
  • 分子式: C151H222N44O40S6?XCF3COOH
  • 分子量: 3486
  • 纯度: >98%
  • 溶解度: Water: 1 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It induces lysis of mammalian cells when used at a concentration of 25 μg/mL. It also inhibits growth of E. faecalis (ED50 = 100 nM) and clinical isolates of P. aeruginosa (MIC90 = 4 μM). HNP-3 binds to recombinant HIV-1 envelope glycoprotein (gp120) and human CD4 (Kds = 52.8 and 34.9 nM, respectively). It also binds to recombinant, immobilized human surfactant protein D (SP-D; Kd = 55.7 nM) and inhibits focus formation in Madin-Darby canine kidney (MDCK) cells infected with influenza A virus (IAV).

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