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- D-myo-Inositol-1,2,3,6-tetraphosphate (sodium salt)
D-myo-Inositol-1,2,3,6-tetraphosphate (sodium salt)
A synthetic, pure inositol phosphate for signal transduction research
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
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包装价格促销价数量
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100ug￥2275.001820.00- +
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500ug￥10162.008130.00- +
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1mg￥17887.0014310.00- +
- 货号: ajcx18346
- CAS: N/A
- 别名: Ins(1,2,3,6)P4 (sodium salt), 1,2,3,6IP4 (sodium salt)
- 分子式: C6H12O18P4?4Na
- 分子量: 588
- 纯度: ＞98%
- 溶解度: Water: 50 mg/ml
- 储存: Store at -20°C
- 库存: 现货
Background
D-myo-Inositol-1,2,3,6-tetraphosphate (Ins(1,2,3,6)-P4) is one of the many inositol phosphate (InsP) isomers that act as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)-P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)-P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(1,2,3,6)-P3 (tested as the meso compound) is 100-fold less potent than Ins(1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes.
