D-myo-Inositol-1,3,5-triphosphate (sodium salt)

A synthetic, pure phosphoinositol for signal transduction research

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库存: 现货

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数量
100ug

￥712.00

570.00

- +
500ug

￥3262.00

2610.00

- +
1mg

￥5737.00

4590.00

- +

已选 0 种 0 瓶

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货号: ajcx18362
CAS: N/A
别名: Ins(1,3,5)P3 (sodium salt), 1,3,5IP3 (sodium salt)
分子式: C6H12O15P3?3Na
分子量: 486
纯度: >98%
溶解度: Soluble in DMSO
储存: Store at -20°C
库存: 现货

Background

D-myo-Inositol-1,3,5-phosphate (Ins(1,3,5)P3) is a member of the inositol phosphate (InsP) family of second messengers that play a critical role in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(1,3,5)P3 (tested as the meso compound) is 50-fold less potent than Ins(1,4,5)P3 at initiating Ca2+ release when injected into Xenopus oocytes.