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- Calcium Channel
- D-myo-Inositol-2,5,6-triphosphate (sodium salt)
D-myo-Inositol-2,5,6-triphosphate (sodium salt)
A synthetic, pure phosphoinositol for signal transduction research
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
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包装价格促销价数量
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100ug￥1012.00810.00- +
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500ug￥4525.003620.00- +
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1mg￥8050.006440.00- +
- 货号: ajcx18382
- CAS: N/A
- 别名: Ins(2,5,6)P3 (sodium salt), 2,5,6IP3 (sodium salt)
- 分子式: C6H12O15P3?3Na
- 分子量: 486
- 纯度: ＞98%
- 溶解度: PBS (pH 7.2): 50 mg/ml,Water:
- 储存: Store at -20°C
- 库存: 现货
Background
Ins(2,5,6)P3 (sodium salt) is a member of the inositol phosphate (InsP) family of second messengers that play a critical role in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of the Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of calcium channels and an increase in intracellular calcium. Ins(2,5,6)P3 is a less potent inducer of calcium release from permeabilized rat basophilic leukemia cells with an EC50 value of 110 µM compared to Ins(1,4,5)P3, which has an EC50 value of 0.17 µM.
