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A fluorogenic substrate for MMP-1, MMP-2, MMP-7, and MMP-9
Dnp-PLGLWA-DArg-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-2, MMP-7, and MMP-9. The activity of MMP-1, MMP-2, MMP-7, and MMP-9 can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis that removes the N-terminal dinitrophenol (Dnp) group.
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