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  • Ghrelin (rat) (trifluoroacetate salt)
Ghrelin (rat) (trifluoroacetate salt)的可视化放大

Ghrelin (rat) (trifluoroacetate salt)

A peptide hormone

原价
¥3875-5437
价格
3100-4350
Ghrelin (rat) (trifluoroacetate salt)的二维码

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  • 库存: 现货
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  • 货号: ajcx18490
  • CAS: N/A
  • 别名:
  • 分子式: C147H245N45O42?XCF3COOH
  • 分子量: 3314.8
  • 纯度: >98%
  • 溶解度: Water: 1 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growth hormone (GH) secretagogue receptor (GHS-R). It increases intracellular calcium in CHO cells expressing rat GHS-R (EC50 = 2.5 nM) and induces GH release from primary rat pituitary cells (EC50 = 2.1 nM). Ghrelin (10 nM) also reduces glucose-, arginine-, and carbachol-induced insulin release and arginine-induced somatostatin release from perfused rat pancreas. It increases GH plasma levels in anesthetized rats, but does not affect follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin, thyroid-stimulating hormone (TSH), or adrenocorticotropic hormone (ACTH) levels when administered at a dose of 10 μg per animal. Ghrelin increases gastric motility in rats in a dose-dependent manner when administered intracranially into the lateral septum and increases food intake and body weight when administered intracerebroventricularly at a dose of 1 μg per animal.

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