A peptide fragment of histone H3
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Histone H3K9Ac (1-21) is an N-terminal peptide fragment that corresponds to amino acid residues 2-22 of the human histone H3 sequence. Acetylation of histone H3 at lysine 9 is associated with active gene transcription and can recruit the super elongation complex to chromatin through direct binding with the AF9 and ENL subunits. It increases at the IFN-β promoter in HeLa cells upon infection with Sendai virus. Acetylation of histone H3 at lysine 9 decreases following induction of DNA damage in HeLa and U2OS cells.
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