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A substrate-competitive inhibitor of PKCζ activity
PKCθ pseudosubstrate inhibitor is a synthetic peptide that corresponds to amino acid residues of the pseudosubstrate domain of protein kinase Cθ (PKCθ). It selectively, reversibly, and substrate-competitively inhibits PKCθ activity and, thus, is used to delineate the signaling functions of PKCθ, which are thought to be involved in several autoimmune disorders.
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