The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids.
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The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4,5)-P2-fluorescein is a fluorescent probe for any protein with a high-affinity binding interaction with inositol-(4,5)-triphosphate phospholipids, such as PI3K, PTEN, or PH-domain-containing proteins.