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- PtdIns-(5)-P1 (1,2-dioctanoyl) (ammonium salt)
PtdIns-(5)-P1 (1,2-dioctanoyl) (ammonium salt)
A synthetic phosphatidylinositol for signal transduction research
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
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包装价格促销价数量
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100ug￥1037.00830.00- +
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500ug￥4612.003690.00- +
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1mg￥8212.006570.00- +
- 货号: ajcx18950
- CAS: N/A
- 别名: DOPI5P1, Phosphatidylinositol5phosphate C8
- 分子式: C25H46O16P2?2NH4
- 分子量: 700.7
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. Phosphatidylinositol-(5)-P1 (1,2-dioctanoyl) (PtdIns-(5)-P1 (1,2-dioctanoyl)) is a synthetic analog of natural PtdIns featuring C8:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as the natural compound. PtdIns-(5)-P1 can be phosphorylated to di- (PtdIns-P2; PIP2) and triphosphates (PtdIns-P3; PIP3) by phosphoinositol (PI)-specific kinases. Hydrolysis of PtdIns-(4,5)-P2 by PI-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.
