TRAP-6 Peptide (trifluoroacetate salt)
A PAR1 agonist
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5mg￥1837.001470.00- +
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- 货号: ajcx19028
- CAS: N/A
- 别名: Ser-Phe-Leu-Leu-Arg-Asn, Thrombin Receptor Agonist Peptide-6
- 分子式: C34H56N10O9?XCF3COOH
- 分子量: 748.9
- 纯度: ＞98%
- 溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 1 mg/ml
- 储存: Store at -20°C
- 库存: 现货
Background
TRAP-6 peptide is a hexapeptide corresponding to residues 42-47 of protease-activated receptor 1 (PAR1). It acts as an agonist of PAR1, inducing platelet aggregation in human platelet-rich plasma ex vivo (EC50 = 0.8 µM). TRAP-6 (0.3 and 0.6 mg/kg) has a triphasic effect on mean arterial blood pressure (MAP) in anesthetized rats with a short decrease, an increase, and then a longer decrease in MAP following intravenous administration.
