Z-VRPR-FMK (trifluoroacetate salt)
An irreversible inhibitor of MALT1
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包装价格促销价数量
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500ug￥5312.004250.00- +
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1mg￥9750.007800.00- +
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- 货号: ajcx19074
- CAS: N/A
- 别名: Z-Val-Arg-Pro-DL-Arg-FMK
- 分子式: C31H49FN10O6?CF3COOH
- 分子量: 790.8
- 纯度: ＞98%
- 溶解度: Water: Soluble
- 储存: Store at -20°C
- 库存: 现货
Background
Z-VRPR-FMK is a selective, irreversible inhibitor of the paracaspase mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), an endopeptidase that targets BCL10 and reduces NF-κB activation in lymphocytes at 12.5 to 75 µM. Other MALT1 substrates that may be affected by Z-VRPR-FMK are TNFAIP3 and CYLD.
