CAY10737
A turn-on fluorescent probe for carbon monoxide
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包装价格促销价数量
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500ug￥4075.003260.00- +
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1mg￥7350.005880.00- +
- 货号: ajcx19346
- CAS: 2079118-42-4
- 别名:
- 分子式: C30H30NO4
- 分子量: 468.6
- 纯度: ＞98%
- 溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 1 mg/ml
- 储存: Store at -20°C
- 库存: 现货
Background
CAY10737 is a turn-on fluorescent probe for the detection of carbon monoxide (CO).1 It is selective for CO over a variety of anions, amino acids, amines, biothiols, and reactive species. In the presence of palladium (Pd) and CO, CAY10737 undergoes the Pd0-mediated Tsuji-Trost reaction to release a fluorescent compound that has absorption and emission maxima of 678/714 nm, respectively. This fluorescence can be used to detect CO production in vitro and in vivo. CAY10737 has low cytotoxicity, decreasing viability of HeLa cells by less than 25% when used at a concentration of 50 μM with PdCl2 for 24 hours.
参考文献
1. Feng, W., and Feng, H. A readily available colorimetric and near-infrared ?uorescent turn-on probe for detection of carbon monoxide in living cells and animals. Sens. Actuators B Chem. 255(Part 2), 2314-2320 (2018).
