CTOP (trifluoroacetate salt)

一个μ-阿片受体的拮抗剂。

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库存: 现货

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数量
1mg

￥2050.00

1640.00

- +
5mg

￥7650.00

6120.00

- +
10mg

￥13125.00

10500.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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货号: ajcx19362
CAS: N/A
别名: Phe-Cys-Tyr-Trp-Orn-Thr-Pen-Thr
分子式: C50H67N11O11S2? XCF3COOH
分子量: 1062.3
纯度: ＞98%
溶解度: Ethanol: slightly soluble,Water: slightly soluble
储存: Store at -20°C
库存: 现货

Background

CTOP is a peptide antagonist of the μ-opioid receptor (IC₅₀ = 2.8 nM).¹ It is selective for μ-opioid receptors over δ-opioid receptors (IC₅₀ = 13,500 nM) and somatostatin receptors (IC₅₀ = 24,000 nM). CTOP inhibits the antinociceptive effect of morphine in the tail flick test in mice (ED₅₀ = 0.018 nmol) and reverses morphine-induced increases in locomotor activity (ED₅₀ = 0.02 nmol).² It also induces withdrawal symptoms in a mouse model of chronic, but not acute, morphine dependence.

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生命科学

有机化学

无机化学

材料科学

CTOP (trifluoroacetate salt)

CTOP (trifluoroacetate salt)详情

Background

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