Histone H4R3Me2s (1-21)-GGK-biotin (trifluoroacetate salt)

一段带有生物素的组蛋白H4肽片段。

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库存: 现货

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250ug

￥4637.00

3710.00

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货号: ajcx19482
CAS: N/A
别名: Ac-SG-R(me2s)-GKGGKGLGKGGAKRHRKV-GGK(Biotin), Arg(Me2s)3-Histone H4 (1-21)-GGK(Biotin), Histone H4 (1-21) (Arg3me2s)
分子式: C111H197N43O29S ? XCF3COOH
分子量: 2630.1
纯度: ＞98%
溶解度: Water: 1 mg/ml
储存: Store at -20°C
库存: 现货

Background

Histone H4R3Me2s (1-21)-GGK-biotin is a peptide fragment of histone H4 that corresponds to amino acid residues 2-22 of the human H4 sequence. It is symmetrically dimetlated at arginine 3 and biotinylated via a C-terminal GGK linker. Symmetric dimetlation of histone 4 at arginine 3 is associated with transcriptional repression.¹ It can recruit the DNA metltransferase DNMT3a, leading to DNA metlation and further transcriptional repression. Histone H4R3Me2s (1-21)-GGK-biotin has been used as a substrate for the qualitative measurement of jumonji domain containing 1B (JMJD1B) arginine demetlase activity and in dot blot assays to verify antibody specificity.²

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信号通路

生命科学

有机化学

无机化学

材料科学

Histone H4R3Me2s (1-21)-GGK-biotin (trifluoroacetate salt)

Histone H4R3Me2s (1-21)-GGK-biotin (trifluoroacetate salt)详情

Background

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