PAR3 (1-6) amide (human) (trifluoroacetate salt)

PAR1和PAR2的肽激动剂。

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库存: 现货

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5mg

￥9250.00

7400.00

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货号: ajcx19572
CAS: N/A
别名: Proteinase-Activated Receptor 3, TFRGAP-NH2
分子式: C29H46N10O7 ? XCF3COOH
分子量: 646.7
纯度: ＞98%
溶解度: Water: 1 mg/ml
储存: Store at -20°C
库存: 现货

Background

PAR3 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 1 (PAR1) and PAR2 that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR3 and residues 39-44 of the full-length human sequence. PAR3 (1-6) amide activates PAR1 and PAR2 in Jurkat and HEK cells, inducing calcium accumulation in Jurkat cells, which is reduced following desensitization with the PAR1- and PAR2-selective peptide agonist SFLLR-NH₂.¹ It decreases the expression of CDC42 in wild-type, but not PAR3 knockdown, PANC-1 cells and reduces invasion of PANC-1 cells.²

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PAR3 (1-6) amide (human) (trifluoroacetate salt)

PAR3 (1-6) amide (human) (trifluoroacetate salt)详情

Background

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