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  2. Cathepsin
  3. Gly-Arg-AMC (hydrochloride)
  • Gly-Arg-AMC (hydrochloride)
Gly-Arg-AMC (hydrochloride)的可视化放大

Gly-Arg-AMC (hydrochloride)

A fluorogenic substrate for cathepsin C

原价
￥600-10437
价格
￥ 480-8350
Gly-Arg-AMC (hydrochloride)的二维码

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  • 库存: 现货
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  • 货号: ajcx19808
  • CAS: 70274-78-1
  • 别名: Gly-Arg-7-amino-4-methylcoumarin, GR-AMC, GR-7-amino-4-methylcoumarin
  • 分子式: C18H24N6O4.XHCl
  • 分子量: 388.4
  • 纯度: >98%
  • 溶解度: DMF: 30mg/mL,DMSO: 30mg/mL,DMSO:PBS (pH 7.2) (1:1): 0.5mg/mL,Ethanol: 20mg/mL
  • 储存: Store at -20°C
  • 库存: 现货

Background

Gly-Arg-AMC is a fluorogenic substrate for cathepsin C.1 Upon enzymatic cleavage by cathepsin C, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin C activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.



|1. Rubach, J.K., Cui, G., Schneck, J.L., et al. The amino-acid substituents of dipeptide substrates of cathepsin C can determine the rate-limiting steps of catalysis. Biochemistry 51(38), 7551-7568 (2012).

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