Amprenavir-d4

A neuropeptide with diverse biological activities

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库存: 现货

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500ug

￥2587.00

2070.00

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1mg

￥4875.00

3900.00

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货号: ajcx19990
CAS: N/A
别名: 安瑞那韦 d4
分子式: C25H31D4N3O6S
分子量: 509.7
纯度: >98%
溶解度: Acetonitrile: soluble,Methanol: soluble
储存: Store at -20°C
库存: 现货

Background

Amprenavir-d4 is intended for use as an internal standard for the quantification of amprenavir by GC- or LC-MS. Amprenavir is an inhibitor of HIV protease (Ki = 0.04 nM).1 It inhibits the cytopathic effects of HIV-1 in MT-4 cells (IC50 = 150 nM). Formulations containing amprenavir have been used in combination with other antiretroviral agents in the treatment of HIV-1 infection.

|1. Sherrill, R.G., Furfine, E.S., Hazen, R.J., et al. Synthesis and antiviral activities of novel N-alkoxy-arylsulfonamide-based HIV protease inhibitors. Bioorganic & Medicinal Chemistry Letters 15(15), 3560-3564 (2005).