Histone H2AX (134-143) (human) (trifluoroacetate salt)

A neuropeptide with diverse biological activities

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库存: 现货

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1mg

￥4075.00

3260.00

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货号: ajcx20650
CAS: N/A
别名: H-Lys-Lys-Ala-Thr-Gln-Ala-Ser-Gln-Glu-Tyr-OH, KKATQASQEY
分子式: C49H80N14O18 ? XCF3COOH
分子量: 1153.3
纯度: >98%
溶解度: Water: 1 mg/ml
储存: Store at -20°C
库存: 现货

Background

Histone H2AX (134-143) is a C-terminal peptide fragment of histone H2AX that corresponds to amino acid residues 134-143 of the human histone H2AX sequence. Histone H2AX (134-143) is an evolutionarily conserved motif that differentiates histone H2AX from other H2A histones.1 It contains a serine residue that is rapidly phosphorylated upon introduction of DNA double-strand breaks and initiation of DNA fragmentation during apoptosis.

|1. Rogakou, E.P., Nieves-Neira, W., Boon, C., et al. Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139. J. Biol. Chem. 275(13), 9390-9395 (2000).