NSC 15520

An inhibitor of RPA70 dsDNA binding

原价

￥512-3862

价格

￥ 410-3090

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库存: 现货

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产品引用

货号: ajcx20702
CAS: 730960-98-2
别名:
分子式: C24H34O6
分子量: 418.5
纯度: >98%
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
储存: Store at -20°C
库存: 现货

Background

NSC 15520 is an inhibitor of replication protein A 70 (RPA70) dsDNA binding.1 It selectively inhibits dsDNA over ssDNA binding to RPA70 when used at concentrations ranging from 25 to 400 μM. NSC 15520 also inhibits the protein-protein interaction between the cell cycle checkpoint control proteins p53 or Rad9 and RPA70.

|1. Glanzer, J.G., Liu, S., and Oakley, G.G. Small molecule inhibitor of the RPA70 N-terminal protein interaction domain discovered using in silico and in vitro methods. Bioorg. Med. Chem. 19(8), 2589-2595 (2011).

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生命科学

有机化学

无机化学

材料科学

NSC 15520

NSC 15520详情

Background