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A neuropeptide with diverse biological activities
AMPA is the defining agonist for the AMPA subgroup of ionotropic glutamate receptors, which mediate excitatory neurotransmission.1,2 Because AMPA does not interfere with binding sites for kainic acid or NMDA , it can be used to distinguish AMPA receptor-
1.Scannevin, R.H., and Huganir, R.L.Postsynaptic organization and regulation of excitatory synapsesNature Reviews.Neuroscience1133-141(2000) 2.Gouaux, E.Structure and function of AMPA receptorsJournal of Physiology554(2)249-253(2004)
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