(R,S)-AMPA (hydrate)

A neuropeptide with diverse biological activities

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库存: 现货

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10mg

￥2450.00

1960.00

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50mg

￥11012.00

8810.00

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货号: ajcx20950
CAS: N/A
别名: αamino3hydroxy5methyl4Isoxazolepropionic Acid
分子式: C7H10N2O4.XH2O
分子量: 186.2
纯度: >98%
溶解度: Water: 10 mM
储存: Store at Room temperature
库存: 现货

Background

AMPA is the defining agonist for the AMPA subgroup of ionotropic glutamate receptors, which mediate excitatory neurotransmission.^1,2 Because AMPA does not interfere with binding sites for kainic acid or NMDA , it can be used to distinguish AMPA receptor-specific activity that contributes to a neuronal response. (R,S)-AMPA contains an equal mixture of the active (S)-enantiomer and the inactive (R)-enantiomer.

1.Scannevin, R.H., and Huganir, R.L.Postsynaptic organization and regulation of excitatory synapsesNature Reviews.Neuroscience1133-141(2000) 2.Gouaux, E.Structure and function of AMPA receptorsJournal of Physiology554(2)249-253(2004)