An unsaturated long-chain fatty alcohol with diverse biological activities
(Z)-9-Hexadecenol is an unsaturated long chain fatty alcohol that has been found in pheromone gland extracts from H. assulta and has diverse biological activities.1,2,3 It is virucidal against herpes simplex virus 2 (HSV-2) when used at a concentration of 10 mM.2 (Z)-9-Hexadecenol is active against the bacterium S. mutans (MIC = 1.56 μg/ml).3 It decreases flight, upwind, close, landing, and copulatory behavior induced by an H. assulta pheromone blend in male H. assulta moths in a wind tunnel assay.1
1.Xu, M., Guo, H., Hou, C., et al.Olfactory perception and behavioral effects of sex pheromone gland components in Helicoverpa armigera and Helicoverpa assultaSci. Rep.622998(2016) 2.Hilmarsson, H., Kristmundsdóttir, T., and Thormar, H.Virucidal activities of medium- and long-chain fatty alcohols, fatty acids and monoglycerides against herpes simplex virus types 1 and 2: Comparison at different pH levelsAPMIS113(1)58-65(2005) 3.Hattori, M., Miyachi, K., Hada, S., et al.Effects of long-chain fatty acids and fatty alcohols on the growth of Streptococcus mutansChem. Pharm. Bull. (Tokyo)35(8)3507-3510(1987)
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