15(S)-HETE-d8

An internal standard for the quantification of 15(S)-HETE

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库存: 现货

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25ug

￥3000.00

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￥5662.00

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货号: ajcx21122
CAS: 84807-87-4
别名: 15(S)-Hydroxyeicosatetraenoic Acid-d8
分子式: C20H24D8O3
分子量: 328.5
纯度: ＞98%
溶解度: 0.1 M Na2CO3: 2 mg/ml,DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS pH 7.2: 0.8 mg/ml
储存: Store at -20°C
库存: 现货

Background

15(S)-HETE-d₈ contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 15(S)-HETE by GC- or LC-MS. 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes.¹ 15(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis.²

1.Nadel, J.A., Conrad, D.J., Ueki, I.F., et al.Immunocytochemical localization of arachidonate 15-lipoxygenase in erythrocyes, leukocytes, and airway cellsJournal of Clinical Investigation871139-1145(1991) 2.Ramis, I., Roselló-Catafau, J., Bulbena, O., et al.15-Hydroxyeicosatetraenoic acid as a major eicosanoid in nasal secretions: Assay by high-performance liquid chromatographic-radioimmunoassay and gas chromatographic-mass spectrometric proceduresJournal of Chromatography496416-422(1989)

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生命科学

有机化学

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15(S)-HETE-d8

15(S)-HETE-d8详情

Background

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