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- HDAC (Histone deacetylases)
- 7-Bromoheptanoic Acid
7-Bromoheptanoic Acid
A building block
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
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包装价格促销价数量
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1g￥387.00310.00- +
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5g￥1087.00870.00- +
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10g￥1962.001570.00- +
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- 货号: ajcx21522
- CAS: 30515-28-7
- 别名: 7-溴庚酸
- 分子式: C7H13BrO2
- 分子量: 209.1
- 纯度: ＞98%
- 溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:5): 0.16 mg/ml
- 储存: Store at -20°C
- 库存: 现货
Background
7-Bromoheptanoic acid is a building block.1,2 It has been used in the synthesis of azide-based nicotinamide phosphoribosyltransferase (Nampt) inhibitors with anticancer activity and SAHA derivatives that inhibit histone deacetylases (HDACs).
1.Colombano, G., Travelli, C., Galli, U., et al.A novel potent nicotinamide phosphoribosyltransferase inhibitor synthesized via click chemistryJ. Med. Chem.53(2)616-623(2010) 2.Suzuki, T., Nagano, Y., Kouketsu, A., et al.Novel inhibitors of human histone deacetylases: Design, synthesis, enzyme inhibition, and cancer cell growth inhibition of SAHA-based non-hydroxamatesJ. Med. Chem.48(4)1019-1032(2005)
