An amino acid building block
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Boc-L-Arg-OH is an amino acid building block.1,2,3 It has been used in the synthesis of antibacterial peptides and as an in vitro model substrate in the study of methylglyoxal peptide crosslinking via the Maillard reaction.
1.Str?m, M.B., Haug, B.E., Skar, M.L., et al.The pharmacophore of short cationic antibacterial peptidesJ. Med. Chem.46(9)1567-1570(2003) 2.Lederer, M.O., and Klaiber, R.G.Cross-linking of proteins by Maillard processes: Characterization and detection of lysine-arginine cross-links derived from glyoxal and methylglyoxalBioorg. Med. Chem.7(11)2499-2507(1999) 3.Al-Abed, Y., Mitsuhashi, T., Ulrich, P., et al.Novel modifications of Nα-boc-arginine and Nα-CBZ-lysine by methylglyoxalBioorg. Med. Chem. Lett.6(13)1577-1578(1996)
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