A neuropeptide with diverse biological activities
C16 Ganglioside GM1-d9 (d18:1/16:0-d9) is intended for use as an internal standard for the quantification of C16 ganglioside GM1 by GC- or LC-MS. Ganglioside GM1 is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue.1,2 C16 Ganglioside GM1 (d18:1/16:0) is a monosialylated ganglioside that contains a 16-carbon saturated acyl chain. It has been found in the brain of wild-type mice and mice lacking the gene for α-N-acetylneuraminide α-2,8-sialyltransferase (St8sia1null) but not those lacking the gene for β-1,4-N-acetylgalactosaminyltransferase 1 (B4galnt1null).3 [Matreya, LLC. Catalog No. 2057]
1.Kolter, T.Ganglioside biochemistryISRN Biochem.506160(2012) 2.Mocchetti, I.Exogenous gangliosides, neuronal plasticity and repair, and the neurotrophinsCell Mol. Life Sci.62(19-20)2283-2294(2005) 3.Mlinac, K., Fabris, D., Vukeli?, ?., et al.Structural analysis of brain ganglioside acetylation patterns in mice with altered ganglioside biosynthesisCarbohydr. Res.3821-8(2013)
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