Colletodiol

A fungal metabolite with immunosuppressive and antiviral activities

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库存: 现货

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1mg

￥5225.00

4180.00

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货号: ajcx22130
CAS: 21142-67-6
别名: (+)-Colletodiol
分子式: C14H20O6
分子量: 284.3
纯度: >98%
溶解度: Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
储存: Store at -20°C
库存: 现货

Background

Colletodiol is a fungal metabolite that has been found in D. grovesii and has immunosuppressant and antiviral activities.^1,2 It inhibits concanavalin A- or LPS-induced proliferation of isolated mouse splenocytes (IC₅₀s = 12 and 5 µg/ml, respectively).¹ Colletodiol inhibits influenza A viral replication in HeLa-IAV-Luc cells.²

1.Fujimoto, H., Nagano, J., Yamaguchi, K., et al.Immunosuppressive components from an ascomycete, Diplogelasinospora grovesiChem. Pharm. Bull.46(3)423-429(1998) 2.Lai, W., Wang, S., and Ye, X.Colletodiol inhibits the replication of influenza A virus WSN/H1N1 by reducing the activity of viral RNA polymeraseWei Sheng Wu Xue Bao53(12)1334-1339(2013)