D-Ornithine lactam

A building block

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库存: 现货

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数量
50mg

￥712.00

570.00

- +
100mg

￥1375.00

1100.00

- +
250mg

￥3262.00

2610.00

- +
500mg

￥5025.00

4020.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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货号: ajcx22366
CAS: 88763-76-2
别名: R-3-氨基-2-哌啶酮
分子式: C5H10N2O
分子量: 114.1
纯度: >98%
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 10 mg/ml
储存: Store at -20°C
库存: 现货

Background

D-Ornithine lactam is a building block.^1,2 It has been used in the synthesis of hepatitis C virus (HCV) non-structural protein 5B (NS5B) inhibitors, as well as αVβ3 integrin receptor antagonists.

1.Li, P., Dorsch, W., Lauffer, D.J., et al.Discovery of novel allosteric HCV NS5B inhibitors. 2. Lactam-containing thiophene carboxylatesACS Med. Chem. Lett.8(2)251-255(2017) 2.Kubota, D., Ishikawa, M., Ishikawa, M., et al.Tricyclic pharmacophore-based molecules as novel integrin ɑvβ3 antagonists. Part IV: Preliminary control of ɑvβ3 selectivity by meta-oriented substitutionBioorg. Med. Chem.14(12)4158-4181(2006)