Elaidic Acid-d17

A neuropeptide with diverse biological activities

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
1mg

￥800.00

640.00

- +
5mg

￥3600.00

2880.00

- +
10mg

￥6400.00

5120.00

- +
25mg

￥13887.00

11110.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajcx22400
CAS: N/A
别名: C18:1(9E)-d17, 9(E)-Oleic Acid-d17, trans-Oleic Acid-d17
分子式: C18H17D17O2
分子量: 299.6
纯度: >98%
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
储存: Store at -20°C
库存: 现货

Background

Elaidic Acid-d₁₇ is intended for use as an internal standard for the quantification of elaidic acid by GC- or LC-MS. Elaidic acid is a monounsaturated trans fatty acid and the 9-trans isomer of oleic acid that has been found in partially hydrogenated cooking oils.¹ It reduces HHT and HETE formation and increases synthesis of prostaglandin E₂ , PGF_2α , PGD₂ , and thromboxane B₂ induced by arachidonic acid in isolated human platelets. Elaidic acid (0.1-5 mmol/L) induces apoptosis in human umbilical vein endothelial cells (HUVECs).² In vivo, elaidic acid (100 mg/kg) reduces cardiac and hepatic autophagy induced by palmitic acid in mice.³

1.Srivastava, K.C., and Awasthi, K.K.A comparative study on the effect of cis (oleic, linoleic) and trans (elaidic, linoelaidic) fatty acids on the in vitro prostaglandin biosynthesis in human blood platelets from (1-14C) arachidonic acidProstaglandins Leukot. Med. 9(6)669-684(1982) 2.Zapolska-Downar, D., Ko?mider, A., and Naruszewicz, M.Trans fatty acids induce apoptosis in human endothelial cellsJ. Physiol. Pharmacol.56(4)611-625(2005) 3.Sauvat, A., Chen, G., Müller, K., et al.Trans-fats inhibit autophagy induced by saturated fatty acidsEBioMedicine30261-272(2018)