现货大促销，价格低至8折起，量大更优惠，详细咨询客服
安捷凯生物医药，安捷凯化学
全部分类
全部分类
  1. 首页
  2. Reactive oxygen species (ROS)
  3. Fluprostenol-d4
  • Fluprostenol-d4
Fluprostenol-d4的可视化放大

Fluprostenol-d4

A neuropeptide with diverse biological activities

原价
￥737-5912
价格
￥ 590-4730
Fluprostenol-d4的二维码

所有产品仅用于科学研究，我们不为任何个人用途提供产品和服务

询价有惊喜，量大更优惠 点击这里给我发消息

  • 库存: 现货
可选包装 >>>
首页
  • 货号: ajcx22514
  • CAS: N/A
  • 别名: 16mtrifluoromethylphenoxy tetranor Prostaglandin F2αd4
  • 分子式: C23H25D4F3O6
  • 分子量: 462.5
  • 纯度: >98%
  • 溶解度: DMF: >100 mg/ml (from Fluprostenol),DMSO: >100 mg/ml (from Fluprostenol),Ethanol: >100 mg/ml (from Fluprostenol),PBS (7.2): 16 mg/ml (from Fluprostenol)
  • 储存: Store at -20°C
  • 库存: 现货

Background

Fluprostenol-d4 contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of fluprostenol by GC- or LC-mass spectrometry. Fluprostenol is a metabolically stable analog of prostaglandin F2α (PGF2α) with potent FP receptor agonist activity.11,2 It inhibits PGF2α binding to human and rat FP receptors with IC50 values of 3.5 and 7.5 nM, respectively.1,2 Fluprostenol is a much more potent luteolytic agent than PGF2α in rats with a minimum fully effective dose of 270 . g/kg to terminate pregnancy.3 It is also an effective inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 value of 3-10 x 10-11 M.4



1.Dukes, M., Russell, W., and Walpole, A.L.Potent luteolytic agents related to prostaglandin F2αNature250(464)330-331(1974) 2.Lake, S., Gullberg, H., Wahlqvist, J., et al.Cloning of the rat and human prostaglandin F2α receptors and the expression of the rat prostaglandin F2α receptorFEBS Letters355317-325(1994) 3.Abramovitz, M., Boie, Y., Nguyen, T., et al.Cloning and expression of a cDNA for the human prostanoid FP receptorThe Journal of Biological Chemisty2692632-2636(1994) 4.Serrero, G., and Lepak, N.M.Prostaglandin F2α receptor (FP receptor) agonists are potent adipose differentiation inhibitors for primary culture of adipocyte precursors in defined mediumBiochemical and Biophysical Research Communications233(1)200-202(1997)

动态评分

0.0

没有评分数据
没有评价数据
一键回到顶部
展开 收缩
安捷凯在线客服