An internal standard for the quantification of lauric acid
Lauric acid-13C is intended for use as an internal standard for the quantification of lauric acid by GC- or LC-MS. Lauric acid is a medium-chain saturated fatty acid. It has been found at high levels in coconut oil.1 Lauric acid induces the activation of NF-κB and the expression of COX-2, inducible nitric oxide synthase (iNOS), and IL-1α in RAW 264.7 cells when used at a concentration of 25 µM.2
1.Laureles, L.R., Rodriguez, F.M., Rea?o, C.E., et al.Variability in fatty acid and triacylglycerol composition of the oil of coconut (Cocos nucifera L.) hybrids and their parentalsJ. Agric. Food Chem.50(6)1581-1586(2002) 2.Lee, J.Y., Sohn, K.H., Rhee, S.H., et al.Saturated fatty acids, but not unsaturated fatty acids, induced the expression of cyclooxygenase-2 mediated through Toll-like receptor 4J. Biol. Chem.276(20)16683-16689(2001)
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