L-DOPA-d3
An internal standard for the quantification of L-DOPA
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包装价格促销价数量
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250mg￥712.00570.00- +
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500mg￥1375.001100.00- +
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1g￥2600.002080.00- +
- 货号: ajcx22806
- CAS: 53587-29-4
- 别名: 左旋多巴D3
- 分子式: C9H8D3NO4
- 分子量: 200.2
- 纯度: ＞98%
- 溶解度: Water: sparingly soluble
- 储存: Store at -20°C
- 库存: 现货
Background
L-DOPA-d3 is intended for use as an internal standard for the quantification of L-DOPA by GC- or LC-MS. L-DOPA is a metabolic precursor of dopamine that is capable of crossing the blood-brain barrier.1 It is produced from L-tyrosine by tyrosine hydroxylase and metabolized by catechol-O-methyl transferase (COMT). In the brain L-DOPA is converted to dopamine. Formulations containing L-DOPA have been used to increase dopamine concentrations in the brain as a treatment for Parkinson's disease and stroke recovery.
1.Berends, H.I., Nijlant, J.M.M., Movig, K.L.L., et al.The clinical use of drugs influencing neurotransmitters in the brain to promote motor recovery after stroke; a Cochrane systematic reviewEur. J. Phys. Rehabil. Med.45(4)621-630(2009)
