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An internal standard for the quantification of medetomidine
Medetomidine-13C-d3 is intended for use as an internal standard for the quantification of medetomidine by GC- or LC-MS. Medetomidine is an imidazole compound that selectively binds to α2-adrenergic receptors (α2-ARs) over α1-ARs (Kis = 1.08 and 1,800 nM, respectively).1
1.Virtanen, R., Savola, J.M., Saano, V., et al.Characterization of the selectivity, specificity and potency of medetomidine as an α2-adrenoceptor agonistEur. J. Pharmacol.150(1-2)9-14(1988)
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