An internal standard for the quantification of N-acetyl desethylchloroquine
N-acetyl Desethylchloroquine-d4 is intended for use as an internal standard for the quantification of N-acetyl desethylchloroquine by GC- or LC-MS. N-acetyl Desethylchloroquine is a minor metabolite of chloroquine .1,2
1.Brown, N.D., Stermer-Cox, M.G., Poon, B.T., et al.Separation and identification of a plasma and urinary mono-acetylated conjugate of chloroquine in man by ion-pair high-performance liquid chromatographyJ. Chromatogr.309(2)426-430(1984) 2.Kotecka, B.M., Edstein, M.D., and Rieckmann, K.H.Chloroquine bioassay of plasma specimens obtained from soldiers on chloroquine plus doxycycline for malaria prophylaxisInt. J. Parasitol.26(11)1325-1329(1996)
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