A neuropeptide with diverse biological activities
N-acetyl-S-(3-hydroxypropyl)-L-Cysteine-d6 is intended for use as an internal standard for the quantification of N-acetyl-S-(3-hydroxypropyl)-L-cysteine by GC- or LC-MS. N-acetyl-S-(3-hydroxypropyl)-L-Cysteine is a metabolite of acrolein, a respiratory irritant formed during combustion and found in tobacco smoke, that is produced via reduction of the aldehyde group of S-(3-oxopropyl)-N-acetyl cysteine.1 N-acetyl-S-(3-hydroxypropyl)-L-Cysteine can be detected in urine as a biomarker of acrolein exposure.
1.Alwis, K.U., deCastro, B.R., Morrow, J.C., et al.Acrolein exposure in U.S. tobacco smokers and non-tobacco users: NHANES 2005-2006Environ. Health Perspect.123(12)1302-1308(2015)
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