A neuropeptide with diverse biological activities
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Nitenpyram-d3 is intended for use as an internal standard for the quantification of nitenpyram by GC- or LC-MS. Nitenpyram is an agonist of insect nicotinic acetylcholine receptors (nAChRs) that does not act at mammalian nAChRs.1 Nitenpyram is classified as a chloronicotinyl neonicotinoid and has high, short-term efficacy against fleas in dogs and cats when administered orally.2 Formulations containing nitenpyram have been used to control sucking insects on crops and animals.1,2
1.Tomizawa, M., and Casida, J.E.Selective toxicity of neonicotinoids attributable to specificity of insect and mammalian nicotinic receptorsAnnu. Rev. Entomol.48339-364(2003) 2.Vo, D.T., Hsu, W.H., Abu-Basha, E.A., et al.Insect nicotinic acetylcholine receptor agonists as flea adulticides in small animalsJ. Vet. Pharmacol. Ther.33(4)315-322(2010)
5-Iodo-A-85380 dihydrochloride
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