A neuropeptide with diverse biological activities
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Rifapentine-d9 is intended for use as an internal standard for the quantification of rifapentine by GC- or LC-MS. Rifapentine is a long-lasting rifamycin antibiotic that inhibits DNA-dependent RNA polymerases and is effective against Mycobacterium species, including M. tuberculosis, as well as experimental infections caused by S. aureus, S. pyogenes group A, S. pneumoniae, and K. pneumoniae.1,2
1.Arioli, V., Berti, M., Carniti, G., et al.Antibacterial activity of DL 473, a new semisynthetic rifamycin derivativeJ. Antibiot. (Tokyo)34(8)1026-1032(1981) 2.Sharma, S.K., Sharma, A., Kadhiravan, T., et al.Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB.Cochrane Database Syst. Rev.7CD007545(2013)