Rimonabant-d10

An internal standard for the quantification of rimonabant

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500ug

￥3112.00

2490.00

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1mg

￥5537.00

4430.00

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Background

Rimonabant-d₁₀ contains 10 deuterium atoms at the 2, 2', 3, 3', 4, 4', 5, 5', 6, and 6' positions. It is intended for use as an internal standard for the quantification of rimonabant by GC- or LC-MS. Rimonabant, also known as SR141716, was the first selective central cannabinoid (CB₁) receptor inverse agonist (K_i = 1.8 nM) to be developed as an appetite suppressant and anti-obesity drug.¹ It is widely used as a tool to investigate CB receptor properties and the mechanisms by which CB agonists exert their pharmacological effects.

1.Rinaldi-Carmona, M., Barth, F., Héaulme, M., et al.SR141716A, a potent and selective antagonist of the brain cannabinoid receptorFEBS Letters350(2-3)240-244(1994)