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- TNF Receptor
- STING Agonist 12b
STING Agonist 12b
A STING agonist
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
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包装价格促销价数量
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500ug￥800.00640.00- +
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1mg￥1437.001150.00- +
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5mg￥6000.004800.00- +
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10mg￥11212.008970.00- +
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- 货号: ajcx23532
- CAS: 2411100-70-2
- 别名:
- 分子式: C16H15NO2
- 分子量: 253.3
- 纯度: ＞98%
- 溶解度: DMF: 1 mg/ml,DMSO: 1 mg/ml
- 储存: Store at -20°C
- 库存: 现货
Background
STING agonist 12b is an agonist of stimulator of interferon genes (STING).1 It binds to STING (Kd = 26.4 µM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 µM, respectively). STING agonist 12b (40 µM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.
1.Hou, S., Lan, X.-j., Li, W., et al.Design, synthesis and biological evaluation of acridone analogues as novel STING receptor agonistsBioorg. Chem.95103556(2020)
