STING Agonist 12b

A STING agonist

原价

￥800-11212

价格

￥ 640-8970

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产品引用

Cell.Cell host & microbe.November 8, 2023
Cell . MOLECULAR PLANT . 1 February 2023
Cell . Immunity . August 10, 2021
Nature Communications.1413 (2022)
ACS . Nano Lett . April 10, 2023

STING Agonist 12b详情
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Background

STING agonist 12b is an agonist of stimulator of interferon genes (STING).¹ It binds to STING (K_d = 26.4 µM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC₅₀s = 7.45 and 10.23 µM, respectively). STING agonist 12b (40 µM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.

1.Hou, S., Lan, X.-j., Li, W., et al.Design, synthesis and biological evaluation of acridone analogues as novel STING receptor agonistsBioorg. Chem.95103556(2020)

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生命科学

有机化学

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STING Agonist 12b

STING Agonist 12b详情

Background