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  • UR-144 N-(5-hydroxypentyl) metabolite-d5
UR-144 N-(5-hydroxypentyl) metabolite-d5的可视化放大

UR-144 N-(5-hydroxypentyl) metabolite-d5

A neuropeptide with diverse biological activities

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¥1400-8162
价格
1120-6530
UR-144 N-(5-hydroxypentyl) metabolite-d5的二维码

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  • 货号: ajcx23688
  • CAS: N/A
  • 别名: XLR11 N(5hydroxypentyl) metabolited5
  • 分子式: C21H24D5NO2
  • 分子量: 332.5
  • 纯度: >98%
  • 溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

UR-144 N-(5-hydroxypentyl) metabolite-d5 is intended for use as an internal standard for the quantification of UR-144 N-(5-hydroxypentyl) metabolite by GC- or LC-MS. UR-144 is a potent synthetic cannabinoid (CB) that preferentially binds the peripheral CB2 receptor (Ki = 1.8 nM) over the central CB1 receptor (Ki = 150 nM).1 UR-144 N-(5-hydroxypentyl) metabolite is an expected phase I metabolite of UR-144, based on the metabolism of similar cannabimimetics.2,3 This metabolite should be detectable in either serum or urine. The physiological and toxicological properties of this compound have not been tested. This product is intended for forensic and research applications.



1.Frost, J.M., Dart, M.J., Tietje, K.R., et al.Indol-3-ylcycloalkyl ketones: Effects of N1 substituted indole side chain variations on CB2 cannabinoid receptor activityJ. Med. Chem.53(1)295-315(2010) 2.Wintermeyer, A., M?ller, I., Thevis, M., et al.In vitro phase I metabolism of the synthetic cannabimimetic JWH-018Anal. Bioanal. Chem.398(5)2141-2153(2010) 3.Chimalakonda, K.C., Moran, C.L., Kennedy, P.D., et al.Solid-phase extraction and quantitative measurement of omega and omega-1 metabolites of JWH-018 and JWH-073 in human urineAnal. Chem.83(16)6381-6388(2011)

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