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  • Zanamivir-13C,15N2
Zanamivir-13C,15N2的可视化放大

Zanamivir-13C,15N2

An internal standard for the quantification of zanamivir

原价
¥7187-7187
价格
5750-5750
Zanamivir-13C,15N2的二维码

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  • 货号: ajcx23754
  • CAS: 1276528-62-1
  • 别名: 扎那米韦-13C,15N2
  • 分子式: C11[13C]H20N2[15N]2O7
  • 分子量: 335.3
  • 纯度: >98%
  • 溶解度: Water: slightly soluble
  • 储存: Store at -20°C
  • 库存: 现货

Background

Zanamivir-13C,15N2 is intended for use as an internal standard for the quantification of zanamivir by GC- or LC-MS. Zanamivir is a sialic acid analog that inhibits neuraminidase release of newly replicated influenza virus particles.1 It has been shown to selectively inhibit the growth of influenza A and B viruses in plaque reduction assays with IC50 values ranging from 5 to 14 nM and to directly inhibit influenza A and B virus neuraminidases with IC50 values ranging from 0.6 to 7.9 nM in vitro. Intranasal zanamivir administration at 0.4 mg/kg twice daily reduces mortality and viral titers in lung homogenates of mice infected with influenza.



1.Elliott, M.Zanamivir: From drug design to the clinicPhilos. Trans. R. Soc. Lond. B Biol Sci.356(1416)1885-1893(2001)

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